WS_FTP has been one of the most popular FTP clients for years because of its straightforward drag-and-drop, point-and-click interface. It has everything you'd expect in a full-featured FTP client, and more. It can retain sites and log-on once created, display and browse directories on local and remote machines, preserve file date/time on transfer, prevent overwrite of newer files; and resume interrupted transfers. WS_FTP is free to non-commercial users. The commercial version can use folders to manage FTP sites and perform multiple transfers using a DOS prompt. It also includes various utilities to help you to manage and automate your file transfers. A huge Help file is included; although it's mainly of use to FTP novices, experienced users will find plenty of tips to make FTP-ing faster and easier.

WS_FTP is a perennially popular FTP client.